PROGRESS OF CD8+CD25+REGULATORY T CELLS IN DISEASES

Progress of CD8+CD25+regulatory T cells in diseases

Progress of CD8+CD25+regulatory T cells in diseases

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CD8+CD25+Treg can inhibit immune response and induce immune tolerance.This article reviews the saosin baltimore changes and underlying mechanisms of CD8+CD25+Treg in pathogenesis of malignant tumors, autoimmune diseases and other common diseases such as asthma, allergic diseases, type 2 diabetes, and pre-eclampsia.The changes of CD8+CD25+Treg in different diseases are inconsistent, cell counting increased in cmpk bolus malignant diseases but decreased in autoimmune diseases.Further understanding of CD8+CD25+Treg would supporte a basis for the prevention, treatment and improving prognosis of these diseases.

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